The Institute of Molecular Biology at the University of Oregon is an interdisciplinary research community, founded in 1959, dedicated to investigating biological questions at the molecular level. Our collaborative and interactive Institute brings together--from the Departments of Biology, Chemistry, and Physics -- scientists using diverse approaches and state-of-the-art facilities. This rich research environment provides exceptional training opportunities for young scientists.
Evolutionary studies of the Wnt signaling pathway in the marine annelid Platynereis dumerilii. This new and emerging model organism is proving useful for understanding the evolution of developmental pathways that control animal body plans. Shown here are photomicrographs of 38-cell and 49-cell stage embryos. These images show fluorescent staining within fixed embryos stained for beta-catenin (red) and alpha-tubulin (green); views are from the animal pole. Tubulin marks the mitotic spindle, which helps to score cell division. beta-catenin is a key component of the Wnt signaling pathway that controls many developmental processes, including stem cell development, and is mutated in many important human cancers, including colon cancer.Bowerman Lab. For details, see Schneider and Bowerman, Developmental Cell 13, 73-86.
Recent IMB Research Publications
Heterochromatin protein 1 forms distinct complexes to direct histone deacetylation and DNA methylation Nat Struct Mol Biol May 2012News & Views
Selker Lab
RNA binding and RNA remodeling activities of the half-a-tetratricopeptide (HAT) protein HCF107 underlie its effects on gene expressionBarkan Lab
IMB News
Eric Selker has been elected to the National Academy of Sciences! Read more...
The 2011 IMB Newsletter is now available.
Hui Zong has been awarded the Richard T. Jones New Investigator Award from the Medical Research Foundation
Chris Doe has been awarded the Medical Research Foundation Discovery Award
297 Klamath Hall